Will PARP inhibitors protect dopamine-making neurons in humans? These same drugs are currently undergoing clinical trials for breast, ovarian and colorectal cancer, and melanoma. There is reason to believe they may be helpful in Parkinson’s disease as well. Unfortunately, any clinical trials are a long way away.
- Description: “Researchers have brought new clarity to the picture of what goes awry in the brain during Parkinson’s disease and identified a compound that eases the disease’s symptoms in mice.“
- Source Link: http://www.laboratoryequipment.com/news/2013/08/scientists-find-biological-target-combating-parkinsons
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Annette is a fundraising consultant whose husband was recently diagnosed with Parkinson’s. Annette found a team of scientists working on a technology she thinks can stop Parkinson's. She was then able to raise funding for the project from multiple financial donors. And that's how Stop Parkinson's was born.
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Can you please elaborate on what PARP inhibitors are? Their use for breast, ovarian, colorectal cancer and melanoma and their potential for use as neuroprotectors?
Does their utility ressemble the one found in Tasigna (nilotinib)?
Thank you