Skin cells with a genetic defect found in a small number of Parkinson’s cases, specifically autosomal recessive juvenile Parkinson’s disease. Essentially, the mutation makes mitochondria, the cell’s energy factories, sick. Out of 2,000 compounds, the screen found a family of new drugs, including an existing drug called UDCA, that allowed the mitochondria to work again. Very nicely done!
- Description: “New drugs which may have the potential to stop faulty brain cells dying and slow down the progression of Parkinson’s, have been identified by scientists in a pioneering study which is the first of its kind.“
- Source Link: http://www.shef.ac.uk/news/nr/parkinsons-drug-screen-1.305775
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