Inflammatory processes can initiate a “complement cascade” leading to “waves of synaptic destruction that characterize neurodegenerative disease”. It can be inferred from the Stanford study that Parkinson’s disease can indeed be described as an autoimmune disease, as accumulation of the C1q protein, in combination with an inflammatory trigger, creates an immune response that destroys synapses.
- Description: “A healthy person’s brain has thousands (maybe millions) of times as many synapses – contact points that relay signals from one nerve cell to the next – as there are stars in the Milky Way.“
- Source Link: http://scopeblog.stanford.edu/2013/08/13/protein-known-for-initiating-immune-response-may-set-our-brains-up-for-neurodegenerative-disorders/
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Annette is a fundraising consultant whose husband was recently diagnosed with Parkinson’s. Annette found a team of scientists working on a technology she thinks can stop Parkinson's. She was then able to raise funding for the project from multiple financial donors. And that's how Stop Parkinson's was born.
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