Parkinson’s disease may be a failure to see old mitochondria as invading bacteria 1
The same PARK2 mutation that causes some early onset Parkinson’s cases, also leads to greater sensitivity to intracellular bacterial infections.
Tag Archives: autophagy
Will PARP inhibitors protect dopamine-making neurons in humans? 1
Drugs called PARP inhibitors are currently undergoing clinical trials for a number of cancers. Will they be helpful in Parkinson’s disease as well?
Keeping our mitochondria healthy by boosting mitophagy? 2
Keep your mitochondria healthy or this genetic mutation will not take out the trash. Now, how do we boost mitophagy? This may be the key to healthy neurons. Description: “Research has linked the disease to a genetic defect that stops cells clearing out defective mitochondria, tiny metabolic generators that supply energy.“ Source Link: http://www.dailymail.co.uk/health/article-2389706/Parkinsons-disease-caused-genetic-defect-claim-scientists-believe-closer-treating-condition.html?ito=feeds-newsxml posted […]
Parkinson’s Disease As Impaired Autophagy
Clogging the vacuum: How Parkinson’s disease is caused by impaired autophagy. Description: “GENETICS 2013: A study published in March in Nature Neuroscience reported that mutations on the LRRK2 gene, responsible for approximately 15% of Parkinson’s among Ashkenazi Jews, leads to the malfunctioning of a disposal system in the cell that recycles old proteins.“ Source Link: […]