Tag Archives: autophagy

Jeff Coxx

Parkinson’s disease may be a failure to see old mitochondria as invading bacteria

Early onset Parkinson’s subtype may be a failure to see old mitochondria as invading bacteria. It turns out that the same PARK2 mutation that causes some early onset Parkinson’s cases, also leads to greater sensitivity to intracellular bacterial infections. Interestingly, mitochondria were once intracellular bacteria, a billion years ago.

posted on my Facebook page: Parkinson’s News

AIMP2 and PARP1

Will PARP inhibitors protect dopamine-making neurons in humans?

Will PARP inhibitors protect dopamine-making neurons in humans? These same drugs are currently undergoing clinical trials for breast, ovarian and colorectal cancer, and melanoma. There is reason to believe they may be helpful in Parkinson’s disease as well. Unfortunately, any clinical trials are a long way away.

posted on my Facebook page: Parkinson’s News

mitophagy

Keeping our mitochondria healthy by boosting mitophagy?

Keep your mitochondria healthy or this genetic mutation will not take out the trash. Now, how do we boost mitophagy? This may be the key to healthy neurons.

posted on my Facebook page: Parkinson’s News

Parkinson's Mutation

Parkinson’s Disease As Impaired Autophagy

Clogging the vacuum: How Parkinson’s disease is caused by impaired autophagy.

posted on my Facebook page: Parkinson’s News